Wibeto Practice is a REMS-certified provider of SPRAVATO® in Chicago, IL. This FDA-approved nasal spray treatment is administered in a safe, monitored environment, offering relief when other treatments haven't been effective.

SPRAVATO® Treatment at wibeto

About SPRAVATO®

SPRAVATO® (esketamine) is an FDA-approved nasal spray for adults with treatment-resistant depression. See 'Diagnostic & Insurance Qualifications” below to see if you may be a potential candidate.

SPRAVATO® works differently than traditional antidepressants. While most antidepressants work on serotonin, norepinephrine, or dopamine systems, SPRAVATO® targets the N-methyl-D-aspartate (NMDA) receptor, offering a new option for patients who haven't responded adequately to conventional treatments.

At Wibeto Practice in Chicago, we are proud to offer this innovative treatment option as part of our comprehensive approach to mental health care.

SAFE

Administered under direct supervision of healthcare providers in our controlled clinical setting.

SUCCESSFUL

Clinically proven to reduce depressive symptoms in patients who haven’t responded to traditional treatments.

LEGAL

FDA-approved treatment available through certified REMS providers like wibeto

FAST-ACTING

Many participants experience improvement within several weeks of treatment

Who is this for?

  • Treatment-Resistant Depression

  • Depression with Suicidal Thoughts

  • Chronic Depression

  • Depression with Anxiety

  • Depression Following Trauma


Diagnostic & Insurance Qualifications

Diagnostic Eligibility: patients who receive a diagnosis of depression, ‘mild to severe’ (single episode or recurrent), are eligible. There are other factors taken into consideration in the clinical assessment to see if candidacy remains.

BCBS PPO Coverage Requirements:

Patients with Blue Cross Blue Shield PPO insurance can qualify for Spravato® treatment after documenting two failed antidepressant trials. As of January 2025, BCBS updated their policy to align with the FDA's approval of Spravato® as a monotherapy, meaning patients are no longer required to simultaneously take an oral antidepressant alongside Spravato®. This update provides greater flexibility in treatment options, including for patients who have experienced adverse effects from traditional antidepressants or prefer a single treatment approach.

Aetna PPO Coverage Requirements:

Patients with Aetna PPO insurance qualify for Spravato® treatment after documenting two failed antidepressant medication trials. Unlike some other insurance providers, Aetna does not require concurrent use of an oral antidepressant during Spravato® treatment. This means eligible patients can receive Spravato® as a standalone therapy, which may be preferable for individuals who have experienced adverse effects from traditional antidepressants or prefer a single treatment approach.

**criteria can differ by specific plan and state**

Optum/UHC PPO Coverage Requirements:

Patients with Optum/UHC PPO insurance qualify for Spravato® treatment after documenting three failed antidepressant medication trials. Optum requires patients to be simultaneously taking at least one oral antidepressant alongside Spravato® therapy. Patients and providers should be prepared to submit thorough documentation of prior treatment history, including diagnosis confirmation and evidence of inadequate response to previous antidepressant medications, to support the prior authorization process.

Watch real life stories of Spravato® success

The wibeto experience

Our thoughtfully designed space offers comfortable private rooms with cozy power recliners (3 chairs, 1 bed), custom mood lighting, tea light candles, calming water features, and an array of greenery. With a relaxing environment that encourages safety to explore, our team is dedicated to helping you make the most of your experience.

  • “When I was truly in my throes of depression, I would start every day off at like a negative six versus a zero. After I started taking SPRAVATO®, I’m starting off the day waking up neutral, which is the best.”

    Nicole P.

  • “I am in a better place than I have been — maybe ever. I think that’s an amazing gift.”

    Grace

Our SPRAVATO® Team

All of the insurances we accept (BCBS PPO, Aetna PPO, Optum/UHC PPO) cover SPRAVATO® treatments.

Please see the ‘Getting Started’ page for further price breakdown*.

For any questions you may have, please contact Billing through the patient portal or at billing@wibetopractice.com
(you can send the front & back of your insurance card, along with your specific questions to allow us to help you best).

FAQs

Is SPRAVATO® regulated?

We administer SPRAVATO® under the guidelines established by the SPRAVATO® Risk Evaluation and Mitigation Strategy (REMS) protocol, which means we strictly adhere to the policies. We have each patient sign onboarding forms to ensure that we are on the same page in being able to give this prescribed treatments.

Can SPRAVATO® be taken in combination with any other depression medications??

In contrast to the use of many other psychedelics (which are not yet legalized), ketamine does not require you taper off your current psychiatric medications.

How many sessions of SPRAVATO® will I need?

Treatment is administered twice weekly for the first month, once weekly for the second month, and then once weekly or once every two weeks in subsequent months (adjusted based on your clinical response).‍

What are some of the side effects of taking SPRAVATO® ?

It does not have the side effect profile accustom to many of the current antidepressants ie. weight gain, emotional numbing, sexual side effects.

Much of the effects (relaxation, euphoric mood) during the treatment are a natural consequence of the medication, however, some people can experience varying degrees of nausea, drowsiness, and increased blood pressure. After the treatment: a mild disorientation, spaciness can remain.

A clinician is present to address any concerns that may arise, and blood pressure + oxygen are checked before/during/after treatment.

How soon can I drive after using SPRAVATO®?

SPRAVATO® may impair your ability to drive or operate machinery. We require patients to have a ride to and from their appointment and to not engage in activities that require high alertness or motor coordination until the next day after a restful sleep.

I have so many more questions..

We understand this is an important decision.

Please see the SPRAVATO® website here for an extended list of questions.

Given the complexities of each clinic case, we believe is best to first establish care with one of our psychiatry providers to see if you are eligible and to address how this may play a role in your overall mental health and healing.

We can also have you set up a call with our experienced Clinic Manager Anila to go over general information - please text our office at 773.253.9002 and inquire about setting up a 15 minute call.

Book an Appointment

Here at wibeto practice, we will see the full you. We are here for you when you are ready.